Thiolated Hyaluronic Acid (HA-SH)

Synonyms: HA-SH

Blafar’s Fast-Gelling Thiolated Hyaluronic Acid (HA-SH) is a modified form of hyaluronic acid, a naturally occurring glycosaminoglycan and component of extracellular matrix (ECM) making it particularly suited to cell culture, cosmetic and medical device applications. It may be used in conjunction with ECM proteins and biopolymers such as collagen, HB-PEG, or HA-A for many hydrogel-based 3D cell culture and tissue engineering applications.

Specifications available: HA-SH – 450 / 220 / 110 kDa HA raw material & 75 / 50 / 25 % substitution degree (SD). This product is packaged in 2 mL or 10 mL glass vials under argon.

Grade: R&D grade or GMP like*
* Our GMP-like products are manufactured in our ISO Class 7 clean room, located within our ISO 13485 certified facilities

Catalogue Number & Description

HASH0101 – 450 kDa, 75% SD
HASH0102 – 450 kDa, 50% SD
HASH0103 – 450 kDa, 25% SD
HASH0201 – 220 kDa, 75% SD
HASH0202 – 220 kDa, 50% SD
HASH0203 – 220 kDa, 25% SD
HASH0301 – 110 kDa, 75% SD
HASH0302 – 110 kDa, 50% SD
HASH0303 – 110 kDa, 25% SD

If these variants do not meet your required specification, please see our page on customised synthesis

Technical Information

Form: White solid foam
Solubility: Water, PBS
Cytotoxicity: Biocompatible
Applications: Hydrogel preparation, 3D cell culture scaffold, 3D bioprinting, ECM substitute

Thiolated hyaluronic acid is suitable for tissue engineering applications, especially to produce hydrogels in the investigation of wound healing due to its biocompatibility and short gelation time with multi-vinyl cross-linker. Blafar offers a range a HA-SH products with different molecular weight and degree of substitution options.

Storage and Packaging Information

Handling:
Please consult the Material Safety Data Sheet (MSDS) provided for information regarding hazards and safe handling practices.

Conditions for Storage:
Store in original vial until use
Recommended storage temperature ≤-15°C.
Avoid exposure to light and heat.

Shelf-Life:
When stored as recommended, our products have a shelf life of 1 year. Please refer to the Certificate of Analysis for the expiration date.

Special Instructions:
Do not expose to air until use.

Find Out More

Click the links below to browse our company brochure and product leaflet.